Polly
12-18-2007, 01:40 PM
Somehow, I'm not surprised.
http://blogs.webmd.com/adhd-medications-and-treatments/2007/12/boys-and-girls-respond-differently-to.html
Boys and Girls Respond Differently to Ritalin
Previous studies have not found a difference in response to methylphenidate (Ritalin, Concerta, Metadate CD) based on sex. However, a new study of 136 boys and 48 girls aged 6 to 12 did find different responses. Girls are more likely to have inattentive type of ADHD, compared to boys, and are more likely to have co-existing anxiety.
The children were randomized to receive Concerta (a 12-hour preparation), Metadate CD (an 8-hour preparation), or placebo. Girls responded significantly better to both Metadate CD and Concerta than the boys 1 ½ hours after dosing, but their response declined more rapidly than the boys from 6 to 12 hours after dosing. By 12 hours after dosing, boys had a much better response to both drugs.
Because of the steeper decline in response to medications toward the end of the day, girls being treated for ADHD might need special attention at the end of the day, e.g. more structure, supervision, or additional medication.
http://blogs.webmd.com/adhd-medications-and-treatments/2007/12/boys-and-girls-respond-differently-to.html
Boys and Girls Respond Differently to Ritalin
Previous studies have not found a difference in response to methylphenidate (Ritalin, Concerta, Metadate CD) based on sex. However, a new study of 136 boys and 48 girls aged 6 to 12 did find different responses. Girls are more likely to have inattentive type of ADHD, compared to boys, and are more likely to have co-existing anxiety.
The children were randomized to receive Concerta (a 12-hour preparation), Metadate CD (an 8-hour preparation), or placebo. Girls responded significantly better to both Metadate CD and Concerta than the boys 1 ½ hours after dosing, but their response declined more rapidly than the boys from 6 to 12 hours after dosing. By 12 hours after dosing, boys had a much better response to both drugs.
Because of the steeper decline in response to medications toward the end of the day, girls being treated for ADHD might need special attention at the end of the day, e.g. more structure, supervision, or additional medication.